Affordable Access

Publisher Website

Effects of isoproterenol infusions on heart rate variability in patients with panic disorder

Authors
Journal
Psychiatry Research
0165-1781
Publisher
Elsevier
Publication Date
Volume
56
Issue
3
Identifiers
DOI: 10.1016/0165-1781(95)02608-y
Keywords
  • Cardiovascular Function
  • Sympathovagal Ratio
  • Spectral Analysis
  • Anxiety Disorder
  • Adrenergic Receptors
  • Panic Attacks

Abstract

Abstract Some evidence suggests that patients with panic disorder have a decreased cardiac vagal and a relatively higher sympathetic activity. In this study, spectral analysis of the time series of heart rate before and after isoproterenol infusions was used to study heart rate variability in six panic disorder patients and 11 normal control subjects. These preliminary data reveal a significant increase of sympathovagal ratios only in the patient group after isoproterenol administration. The findings suggest a relative increase in cardiac sympathetic and a relative decrease in cardiac vagal function in patients with panic disorder during isoproterenol infusions.

There are no comments yet on this publication. Be the first to share your thoughts.