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Syntheses and preliminary pharmacological evaluation of the two epimers of the 5-F2t-isoprostane

Authors
Publisher
Elsevier Ltd
Publication Date
Volume
11
Issue
18
Identifiers
DOI: 10.1016/s0960-894x(01)00473-5

Abstract

Abstract The total synthesis of the 5-F 2t-isoprostane 1 and its 5-epimer 2 from diacetone- d-glucose is described. We report preliminary data on the vascular properties of these compounds.

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