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X-ray-induced translocations in marmoset (Callithrix jacchus) stem-cell spermatogonia

Authors
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
0027-5107
Publisher
Elsevier
Publication Date
Volume
129
Issue
2
Identifiers
DOI: 10.1016/0027-5107(84)90155-6

Abstract

Abstract The induction of reciprocal translocations in spermatogonial stem cells of marmosets ( Callithrix jacchus) was studied after irradiation with different doses X-rays (50, 100 and 200 rad) via spermatocyte analysis many cell generations later. The obtained results show a dose-effect relationship with clear saturation effects at 200 rad. The recorded frequencies of translocations were much lower than those reported for closely related marmosets ( Saguinus fuscicollis and Saguinos oedipus). Possible reasons for this difference are discussed.

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