Affordable Access

Publisher Website

Hypoxic protection against fast neutrons of different energies—A review

European Journal of Cancer (1965)
Publication Date
DOI: 10.1016/0014-2964(71)90009-0
  • Mathematics
  • Medicine


Abstract The differences between the dependence of Oxygen Enhancement Ratio (OER) on fast neutron energy in P- 388 murine leukaemia cells, and the lack of effect of neutron energy upon OER reported in human kidney-derived T- 1 cells correlate well (perhaps fortuitously) with differences in responses of the same cells to irradiation with monoenergetic track-segments of beams of deuterons and alpha-particles whose ionization densities (LET) are known. However, irradiation of the P- 388 tumour cells with collimated beams of fast neutrons at 10 cm depth in a tissue-equivalent phantom yields OER values lower than predicted by consideration of average LET and relatively independent of neutron energy. For irradiation from a planar array of neutron-emitting 25 2 Cf sources in a tissue-equivalent holder simulating a brachytherapy implant, the OER is disappointingly high (2 · 0), although still significantly lower than for irradiation with 2 26 Ra gamma rays in the same geometry.

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times

More articles like this

Hypoxic protection against fast neutrons of differ...

on European journal of cancer May 1971

Survival of cultured human cells after irradiation...

on International journal of radia... 1968

Absence of AET protection against fast neutrons: c...

on Radiation and environmental bi... 1981

Letter: Chemical protection of cultured mammalian...

on International journal of radia... March 1975
More articles like this..