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Significance of cellular enzyme activity at nonabsorbable suture implant sites: silk, polyester, and polypropylene

Authors
Journal
Journal of Surgical Research
0022-4804
Publisher
Elsevier
Publication Date
Volume
19
Issue
2
Identifiers
DOI: 10.1016/0022-4804(75)90117-1
Disciplines
  • Biology
  • Chemistry

Abstract

Abstract Quantitative enzyme histochemical procedures provide a valuable and objective approach to the problem of evaluating the histocompatibility of surgical suture and implant materials with increased confidence. In this study the silk suture evoked a higher level of hydrolytic enzyme activity at the implant site than did either the braided polyester suture or the monofilament polypropylene suture, suggesting that the latter are more inert materials over extended periods of implantation. It is considered that greater consistency and reproducibility would accrue in the evaluation of suture materials by the application of a system based on cell function, rather than a continued sole reliance on the more subjective morphologic examination of the implant sites.

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