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Microbiota, Disease, and Back to Health: A Metastable Journey

Authors
Journal
Science Translational Medicine
1946-6234
Publisher
American Association for the Advancement of Science (AAAS)
Publication Date
Volume
4
Issue
137
Identifiers
DOI: 10.1126/scitranslmed.3004184
Disciplines
  • Medicine

Abstract

Alterations in the composition of the commensal microbiota have been observed in many complex diseases. Understanding the basis for these changes, how they relate to disease risk or activity, and the mechanisms by which the symbiotic state of colonization resistance and host homeostasis is restored is critical for future therapies aimed at manipulating the microbiota.

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