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B – Flow assessment of femoral artery as predictor of coronary artery disease in patients evaluated for chest pain by radionuclide myocardial perfusion scintigraphy

  • Avramovski, Petar
  • Avramovska, Maja1
  • Servini, Zaklina2
  • Nikleski, Zorica3
  • Veljanovska, Keti2
  • Mihajlova, Snezana2
  • Sotiroski, Kosta4, 5
  • Sikole, Aleksandar6
  • 1 Department of Gynecology, Clinical Hospital, Bitola, Macedonia
  • 2 Department of Nuclear Medicine, Clinical Hospital, Bitola, Macedonia
  • 3 Advanced Torrens University, Australia
  • 4 Department of Economic Statistics, Faculty of Economics, Prilep, Macedonia
  • 5 Department of Statistics, University St. Kliment Ohridski, Bitola, Macedonia
  • 6 Department of Nephrology, Medical Faculty, University St. Curil and Methodius, Skopje, Macedonia
Published Article
World Journal of Nuclear Medicine
Wolters Kluwer - Medknow
Publication Date
Dec 18, 2019
DOI: 10.4103/wjnm.WJNM_74_18
PMID: 31933556
PMCID: PMC6945363
PubMed Central


In the evaluation of patients with suspected coronary artery disease (CAD), the presence of the superficial femoral artery (SFA) plaque is more informative than a carotid plaque and at least as informative as coronary plaque in the identification of coronary death individuals. In 60 patients with chest pain with a normal electrocardiogram, B-flow ultrasound estimation of SFA plaque and radionuclide myocardial perfusion scintigraphy (MPS) estimation for CAD was performed. We found significant positive correlations between age and SFA plaque score (PS) ( P = 0.0084), myocardial ischemia in rest and SFA PS ( P < 0.0001), and between transient ischemic dilation (TID) and SFA PS ( P = 0.0069), too. The TID correlates only with myocardial ischemia in rest ( P = 0.0022) and SFA PS ( P = 0.0069). The results we got by the receiver operating characteristics (ROC) curve analysis with TID/without TID were the area under curve (0.704, P = 0.0038). The multiple regression analysis showed standardized coefficient β coefficients for SFA PS and TID (3.4577 and 1.9903, P < 0.001 and P = 0.0021), respectively. By proven correlative relationship of SFA atherosclerotic plaques and CAD, we can use B-flow as a screening method for triage of patients with chest pain before being sent to the assessment of coronary circulation with radionuclide MPS.

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