Affordable Access

deepdyve-link
Publisher Website

B cell memory: understanding COVID-19

Authors
  • Quast, Isaak1
  • Tarlinton, David1
  • 1 Department of Immunology and Pathology, Monash University, 89 Commercial Road, Melbourne, VIC 3004, Australia
Type
Published Article
Journal
Immunity
Publication Date
Jan 23, 2021
Volume
54
Issue
2
Pages
205–210
Identifiers
DOI: 10.1016/j.immuni.2021.01.014
PMID: 33513337
PMCID: PMC7826135
Source
PubMed Central
License
Unknown

Abstract

Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defense strategy and underlie virtually all vaccine success. Here, we explain how B cell memory is generated by infection and vaccination, what influences its efficacy and its persistence, and how characterizing these parameters in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will help achieve protective immunity through vaccination.

Report this publication

Statistics

Seen <100 times