Affordable Access

Axonal transport of gangliosides in the goldfish optic nerve.

Authors
  • Forman, D S
  • Ledeen, R W
Type
Published Article
Journal
Science (New York, N.Y.)
Publication Date
Aug 18, 1972
Volume
177
Issue
4049
Pages
630–633
Identifiers
PMID: 5049309
Source
Medline
License
Unknown

Abstract

Radioactive glucosamine and N-acetylmannosamine injected into the goldfish eye are incorporated into gangliosides that undergo rapid axonal transport to the optic nerve terminals. All ganglioside fractions are labeled. These data provide the first evidence that axonal transport has a role in neuronal ganglioside function and metabolism.

Report this publication

Statistics

Seen <100 times