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Automated segmentation and characterization of choroidal vessels in high-penetration optical coherence tomography.

Authors
  • Duan, Lian
  • Hong, Young-Joo
  • Yasuno, Yoshiaki
Type
Published Article
Journal
Optics Express
Publisher
The Optical Society
Publication Date
Jul 01, 2013
Volume
21
Issue
13
Pages
15787–15808
Identifiers
DOI: 10.1364/OE.21.015787
PMID: 23842365
Source
Medline
License
Unknown

Abstract

An automated choroidal vessel segmentation and quantification method for high-penetration optical coherence tomography (OCT) was developed for advanced visualization and evaluation of the choroidal vasculature. This method uses scattering OCT volumes for the segmentation of choroidal vessels by using a multi-scale adaptive threshold. The segmented choroidal vessels are then processed by multi-scale morphological analysis to quantify the vessel diameters. The three-dimensional structure and the diameter distribution of the choroidal vasculature were then obtained. The usefulness of the method was then evaluated by analyzing the OCT volumes of normal subjects.

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