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Automated Measurement of Cobblestone Morphology for Characterizing Stem Cell Derived Retinal Pigment Epithelial Cell Cultures.

Authors
  • Joshi, Rohini1
  • Mankowski, Walter1
  • Winter, Mark1
  • Saini, Janmeet S2
  • Blenkinsop, Timothy A3
  • Stern, Jeffrey H2
  • Temple, Sally2
  • Cohen, Andrew R1
  • 1 1 Department of Electrical and Computer Engineering, Drexel University , Philadelphia, Pennsylvania.
  • 2 2 Neural Stem Cell Institute , Rensselaer, New York.
  • 3 3 Developmental and Regenerative Biology, Mount Sinai Hospital , New York, New York.
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
Jun 01, 2016
Volume
32
Issue
5
Pages
331–339
Identifiers
DOI: 10.1089/jop.2015.0163
PMID: 27191513
Source
Medline
License
Unknown

Abstract

Two image analysis techniques enable robust and accurate characterization of the cobblestone morphology that is indicative of viable RPE cultures for therapeutic applications.

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