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Autoimmune thrombocytopenia in response to splenectomy in cirrhotic patients with accompanying hepatitis C.

Authors
  • Sekiguchi, Tetsuro
  • Nagamine, Takeaki
  • Takagi, Hitoshi
  • Mori, Masatomo
Type
Published Article
Journal
World Journal of Gastroenterology
Publisher
Baishideng Publishing Group Co
Publication Date
Feb 28, 2006
Volume
12
Issue
8
Pages
1205–1210
Identifiers
PMID: 16534872
Source
Medline
License
Unknown

Abstract

Our data indicate that the autoimmune mechanism plays an important role in thrombocytosis complicated by HCV-positive cirrhosis. In addition, splenectomy may impair T cells function through, at least in part, a reduction of CD4/CD8 ratio, consequently suppressing PAIgG production.

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