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[Autoimmune pancreatitis].

Authors
  • Vonlaufen, Alain
  • Frossard, Jean-Louis
Type
Published Article
Journal
Revue médicale suisse
Publication Date
Sep 08, 2010
Volume
6
Issue
261
Pages
1662–1666
Identifiers
PMID: 20939400
Source
Medline
License
Unknown

Abstract

Autoimmune pancreatitis (ALP) represents a distinct form of chronic pancreatitis initially described in Japan but now reported worldwide. AIP often presents with obstructive jaundice/pancreatic mass as well as pancreatic exocrine and endocrine insufficiency. Histologically, it is characterised by a lymphoplasmacytic infiltrate with fibrosis. The disease responds readily to steroids in 70-80% of cases. Given the absence of unified diagnostic criteria, the diagnosis of AIP proves difficult. In particular, distinguishing ALP from pancreatic or biliary cancer remains a challenging task. In order to avoid unnecessary resections for an otherwise benign and easily treatable condition, it is urgent to refine diagnostic criteria and to reach an international consensus.

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