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Autocrine growth inhibition by transforming growth factor beta-1 (TGFbeta-1) in human neuroendocrine tumour cells.

Authors
  • Wimmel, A
  • Wiedenmann, B
  • Rosewicz, S
Type
Published Article
Journal
Gut
Publication Date
Sep 01, 2003
Volume
52
Issue
9
Pages
1308–1316
Identifiers
PMID: 12912863
Source
Medline
License
Unknown

Abstract

Neuroendocrine tumour cells of the gastroenteropancreatic tract are subject to paracrine and autocrine growth inhibition by TGFbeta-1, which may account in part for the low proliferative index of this tumour entity.

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