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Auto--antibodies to DNA in the sera of Nigerians attending a rheumatic diseases clinic.

Authors
  • Adelowo, O O
  • Salimonu, L S
  • Arinola, O G
Type
Published Article
Journal
African journal of medicine and medical sciences
Publication Date
Jan 01, 1998
Volume
27
Issue
3-4
Pages
173–176
Identifiers
PMID: 10497642
Source
Medline
License
Unknown

Abstract

The presence of auto-antibodies to DNA in the sera of 199 Nigerians: 46 with osteoarthritis, 16 with rheumatoid arthritis, 5 with SLE, 18 with chronic hepatitis, 24 peptic ulcer disease and 90 blood donors were assayed using a haemagglutination method. The positivity rates of auto-antibodies to DNA in these subjects were comparable [X2 = 1.56, P > 0.10]. The results of this study shows that the presence of auto-antibodies to DNA is not a reliable diagnostic index for auto-immune phenomena.

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