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Auditory responses in cochlear implant users with and without GJB2 deafness.

Authors
  • 1
Type
Published Article
Journal
The Laryngoscope
0023-852X
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
116
Issue
2
Pages
317–327
Identifiers
PMID: 16467727
Source
Medline

Abstract

Results suggest more consistent spiral ganglion survival along the length of the cochlea in GJB2-related HL as compared with non-GJB2-related HL, which appears to involve a decreasing gradient of spiral ganglion survival from the apex to the base of the cochlea. Our findings support our premise that in GJB2-related HL, dysfunction of gap junctions likely occurs to a similar degree in the apical and basal regions of the cochlea. This knowledge might be used to customize implantable devices for patients with HL in the future.

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