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Audiological monitoring for ototoxic tuberculosis, human immunodeficiency virus and cancer therapies in a developing world setting.

Authors
  • Harris, T
  • Peer, S
  • Fagan, J J
Type
Published Article
Journal
The Journal of Laryngology & Otology
Publisher
Cambridge University Press
Publication Date
Jun 01, 2012
Volume
126
Issue
6
Pages
548–551
Identifiers
DOI: 10.1017/S0022215112000357
PMID: 22459550
Source
Medline
License
Unknown

Abstract

Ototoxic drugs are widely used in the developing world, without audiological monitoring. Epidemiological data on ototoxic deafness are lacking for developing countries. The public health aspect of ototoxicity is often overlooked, to the detriment of the individual patient. This paper reviews ototoxic hearing loss, particularly in sub-Saharan Africa, and also assesses the impact of treatments for tuberculosis, cancer and human immunodeficiency virus (the latter including highly active antiretroviral therapy) on ototoxic hearing loss. The paper also discusses obstacles to audiological monitoring for ototoxicity in the developing world, and the potential of audiology screening using applications for mobile devices.

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