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Atrioventricular node ablation in Langendorff-perfused porcine hearts using carbon ion particle therapy: methods and an in vivo feasibility investigation for catheter-free ablation of cardiac arrhythmias.

Authors
  • Lehmann, H Immo
  • Richter, Daniel
  • Prokesch, Hannah
  • Graeff, Christian
  • Prall, Matthias
  • Simoniello, Palma
  • Fournier, Claudia
  • Bauer, Julia
  • Kaderka, Robert
  • Weymann, Alexander
  • Szabó, Gábor
  • Sonnenberg, Karin
  • Constantinescu, Anna M
  • Johnson, Susan B
  • Misiri, Juna
  • Takami, Mitsuru
  • Miller, Robert C
  • Herman, Michael G
  • Asirvatham, Samuel J
  • Brons, Stephan
  • And 6 more
Type
Published Article
Journal
Circulation Arrhythmia and Electrophysiology
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Apr 01, 2015
Volume
8
Issue
2
Pages
429–438
Identifiers
DOI: 10.1161/CIRCEP.114.002436
PMID: 25609687
Source
Medline
Keywords
License
Unknown

Abstract

This is the first report of the application of a (12)C beam for ablation of cardiac tissue to treat arrhythmias. Catheter-free ablation using 12C beams is feasible and merits exploration in intact animal studies as an energy source for arrhythmia elimination.

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