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Associations of proinflammatory cytokine levels with lipid profiles, growth, and body composition in HIV-infected children initiating or changing antiretroviral therapy.

Authors
  • Cervia, Joseph S
  • Chantry, Caroline J
  • Hughes, Michael D
  • Alvero, Carmelita
  • Meyer, William A 3rd
  • Hodge, Janice
  • Borum, Peggy
  • Moye, Jack Jr
  • Spector, Stephen A
Type
Published Article
Journal
The Pediatric Infectious Disease Journal
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Dec 01, 2010
Volume
29
Issue
12
Pages
1118–1122
Identifiers
DOI: 10.1097/INF.0b013e3181ed9f4c
PMID: 20631646
Source
Medline
License
Unknown

Abstract

In HIV-infected children initiating or changing ART, PIC were detectable at baseline and decreased over 48 weeks. Better immunologic responses were associated with greater reductions in TNF-α and IL-6. Reductions in TNF-α were associated with improved total/HDL cholesterol ratio.

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