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Associations between inflammatory markers, traditional risk factors, and complications in patients with type 2 diabetes mellitus.

Authors
  • Streja, Dan
  • Cressey, Pamela
  • Rabkin, Simon W
Type
Published Article
Journal
Journal of Diabetes and its Complications
Publisher
Elsevier
Publication Date
Jan 01, 2003
Volume
17
Issue
3
Pages
120–127
Identifiers
PMID: 12738395
Source
Medline
License
Unknown

Abstract

In patients with diabetes: (1) the two markers, FIB and CRP, are interrelated; (2) FIB is significantly associated with presence of microvascular disease, independent of CRP; (3) CRP is strongly associated with metabolic factors but not with complications of diabetes, independently of FIB; (4) statins and HRT were divergently associated with CRP and FIB as HRT was associated with lower FIB and higher CRP, while statins showed the reverse association; and (5) CRP and FIB provide different information about the characteristics and consequences of diabetes mellitus because of divergent associations with biological indicators and therapeutic agents.

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