Affordable Access

deepdyve-link
Publisher Website

Associations between Infant and Parent Characteristics and Measures of Family Well-Being in Neonates with Seizures: A cohort study

Authors
  • Franck, Linda S.1
  • Shellhaas, Renée A.2
  • Lemmon, Monica3
  • Sturza, Julie2
  • Soul, Janet S.4
  • Chang, Taeun5
  • Wusthoff, Courtney J.6
  • Chu, Catherine J.7
  • Massey, Shavonne L.8
  • Abend, Nicholas S.8, 9
  • Thomas, Cameron10
  • Rogers, Elizabeth E.11
  • McCulloch, Charles E.12
  • Grant, Katie13
  • Grossbauer, Lisa14
  • Pawlowski, Kamil15
  • Glass, Hannah C.16
  • 1 Department of Family Health Care Nursing, University of California San Francisco, San Francisco, CA;
  • 2 Department of Pediatrics, University of Michigan, Ann Arbor, MI;
  • 3 Division of Pediatric Neurology and Developmental Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, NC;
  • 4 Department of Neurology, Boston Children’s Hospital, Harvard Medical School, Boston, MA;
  • 5 Department of Neurology, Children’s National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC;
  • 6 Departments of Neurology & Pediatrics, Stanford University, Palo Alto, CA;
  • 7 Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA;
  • 8 Departments of Neurology and Pediatrics, Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA;
  • 9 Departments of Anesthesia & Critical Care Medicine, Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA;
  • 10 Department of Pediatrics, University of Cincinnati, Cincinnati, OH, and Division of Neurology, Cincinnati Children’s Hospital Medical Center;
  • 11 Department of Pediatrics, UCSF Benioff Children’s Hospital, University of California San Francisco, San Francisco, CA;
  • 12 Department of Epidemiology & Biostatistics; University of California San Francisco, San Francisco, CA;
  • 13 Parent Partner, Cincinnati Children’s Hospital Medical Center;
  • 14 Parent Partner, Children’s Hospital of Philadelphia;
  • 15 Parent Partner, UCSF Benioff Children’s Hospital;
  • 16 Departments of Neurology & Pediatrics; UCSF Benioff Children’s Hospital, University of California San Francisco, San Francisco, CA.
Type
Published Article
Journal
The Journal of pediatrics
Publication Date
Jun 01, 2020
Volume
221
Pages
64–71
Identifiers
DOI: 10.1016/j.jpeds.2020.02.024
PMID: 32446494
PMCID: PMC7336525
Source
PubMed Central
Keywords
License
Unknown

Abstract

Objective To characterize and determine risk factors for key dimensions of well-being at hospital discharge in families of neonates with acute symptomatic seizures. Study Design This prospective, observational cohort study enrolled 144 parent-infant dyads among neonates with acute symptomatic seizures from nine pediatric hospitals of the Neonatal Seizure Registry . One parent per family completed discharge surveys, which included measures of anxiety and depression, health related quality of life, and impact on the family. Multivariable regression analyses adjusted for site were constructed to examine parent and infant characteristics associated with well-being. Results At discharge, 54% of parents reported symptoms of anxiety and 32% reported symptoms of depression. Parents of infants with hypoxic-ischemic encephalopathy reported more depression and worse quality of life (QOL) than parents of infants with other seizure etiologies. Parental QOL was also lower with greater infant age at discharge. A higher level of maternal education was associated with greater impact on the family. All of these differences were medium to large effect sizes, ranging from 0.52 to 0.78. Conclusions Symptoms of anxiety and depression are common in parents of infants with neonatal seizures and several parent and infant characteristics are associated with poorer parental quality of life and family well-being. These findings are a call to action to improve mental health screening and services for parents of infants with neonatal seizures.

Report this publication

Statistics

Seen <100 times