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Associations between ECG changes and echocardiographic findings in patients with acute non-ST elevation myocardial infarction.

Authors
  • Tuohinen, Suvi Sirkku1
  • Rankinen, Jani2
  • Skyttä, Tanja3
  • Huhtala, Heini4
  • Virtanen, Vesa2
  • Kellokumpu-Lehtinen, Pirkko-Liisa3
  • Raatikainen, Pekka5
  • Nikus, Kjell2
  • 1 Heart and Lung Center, Helsinki University Central Hospital and Helsinki University; Faculty of Medicine and Life Sciences, University of Tampere, Finland; Heart Center, Tampere University Hospital, Finland. Electronic address: [email protected] , (Finland)
  • 2 Faculty of Medicine and Life Sciences, University of Tampere, Finland; Heart Center, Tampere University Hospital, Finland. , (Finland)
  • 3 Faculty of Medicine and Life Sciences, University of Tampere, Finland; Department of Oncology, Tampere University Hospital, Finland. , (Finland)
  • 4 Faculty of Social Sciences, University of Tampere, Finland. , (Finland)
  • 5 Heart and Lung Center, Helsinki University Central Hospital and Helsinki University.
Type
Published Article
Journal
Journal of electrocardiology
Publication Date
Jan 01, 2018
Volume
51
Issue
2
Pages
188–194
Identifiers
DOI: 10.1016/j.jelectrocard.2017.11.007
PMID: 29174705
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

ST segment depression (STD) and T wave inversion (TWI) are typical electrocardiographic (ECG) findings in non-ST elevation myocardial infarction (NSTEMI). In ST elevation myocardial infarction, ST changes represent transmural ischemia. The pathophysiological mechanisms of the ECG changes in NSTEMI are unclear. We studied the associations between ECG and the echocardiographic findings in NSTEMI patients. Twenty patients with acute NSTEMI were recruited during their hospital stay. A comprehensive echocardiography study was performed. The findings were compared with blinded ECG analyses. Nine (45%) patients had STD, and 16 (85%) patients had TWI. In multivariable analysis, STD was independently associated with a lower global early diastolic strain rate (β=-5.061, p=0.033). TWI was independently associated with lower circumferential strain (β=0.132, p=0.032). The typical ECG changes in NSTEMI patients were associated with subtle echocardiographic changes. STD was related to changes in diastolic function, and TWI was associated with systolic deterioration. Copyright © 2017 Elsevier Inc. All rights reserved.

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