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Association of Systemic Inflammatory and Anti-inflammatory Responses with Adverse Outcomes in Acute Pancreatitis: Preliminary Results of an Ongoing Study.

Authors
  • Sharma, Deepesh1
  • Jakkampudi, Aparna2, 3
  • Reddy, Ratnakar2
  • Reddy, Panyala Balakumar2
  • Patil, Aasish1
  • Murthy, H V V4
  • Rao, G Venkat5
  • Reddy, D Nageshwar1
  • Talukdar, Rupjyoti6, 7, 8, 9
  • 1 Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Somajiguda, Hyderabad, Telangana, 500082, India. , (India)
  • 2 Division of Basic and Translational Sciences, Asian Healthcare Foundation, Hyderabad, India. , (India)
  • 3 Wellcome DBT India Alliance Laboratories, Asian Healthcare Foundation, Hyderabad, India. , (India)
  • 4 Department of Biostatistics, Asian Institute of Gastroenterology, Hyderabad, India. , (India)
  • 5 Department of Surgical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India. , (India)
  • 6 Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Somajiguda, Hyderabad, Telangana, 500082, India. [email protected] , (India)
  • 7 Division of Basic and Translational Sciences, Asian Healthcare Foundation, Hyderabad, India. [email protected] , (India)
  • 8 Wellcome DBT India Alliance Laboratories, Asian Healthcare Foundation, Hyderabad, India. [email protected] , (India)
  • 9 Pancreas Research Group, Asian Healthcare Foundation, 6-3-661 Somajiguda, Hyderabad, Telangana, 500082, India. [email protected] , (India)
Type
Published Article
Journal
Digestive Diseases and Sciences
Publisher
Springer-Verlag
Publication Date
Dec 01, 2017
Volume
62
Issue
12
Pages
3468–3478
Identifiers
DOI: 10.1007/s10620-017-4813-6
PMID: 29080144
Source
Medline
Keywords
License
Unknown

Abstract

Our study objectively demonstrates significant association of ESAP and early mortality with primary cytokine response, and development of IPN with persistent HLA-DR down-regulation.

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