Association of Sitting Time With All-Cause and Cardiovascular Mortality: How Does Frailty Modify This Association?
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Authors
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Diaz-Toro, Felipe1, 2
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Nazzal Nazal, Carolina3
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Nazar, Gabriela4
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Diaz-Martinez, Ximena5
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Concha-Cisternas, Yeny6, 7
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Celis-Morales, Carlos8
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Petermann-Rocha, Fanny8, 9
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1
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
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2
Facultad de Enfermería, Universidad Andres Bello, Santiago, Chile.
,
(Chile)
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3
Escuela de Salud Pública, Facultad de Medicina Universidad de Chile, Santiago, Chile.
,
(Chile)
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4
Departamento de Psicología y Centro de Vida Saludable, Universidad de Concepción, Concepción, Chile.
,
(Chile)
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5
Grupo de Investigación Calidad de Vida, Universidad del Biobío, Chillán, Chile.
,
(Chile)
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6
Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Talca, Chile.
,
(Chile)
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7
Pedagogía en Educación Física, Facultad de Educación, Universidad Autónoma de Chile, Talca, Chile.
,
(Chile)
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8
Human Performance Lab, Education, Physical Activity and Health Research Unit, University Católica del Maule, Talca, Chile.
,
(Chile)
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9
Centro de Investigación Biomédica, Facultad de Medicina, Universidad Diego Portales, Santiago, Chile.
,
(Chile)
- Type
- Published Article
- Journal
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Journal of aging and physical activity
- Publication Date
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Dec 21, 2023
- Volume
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32
- Issue
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2
- Pages
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236–243
- Identifiers
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DOI: 10.1123/japa.2023-0105
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PMID: 38134903
- Source
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Medline
- Keywords
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- Language
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English
- License
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Unknown
Abstract
To investigate how frailty modifies the association of sitting time with all-cause and cardiovascular mortality in Chilean adults. This prospective study included 2,604 participants aged ≥35 from the Chilean National Health Survey 2009-2010. Sitting time was self-reported, while frailty was assessed using a 36-item Frailty Index. Sitting time was categorized as low, medium, and high. Cox proportional hazard models were used to estimate the risk of mortality stratified for the sitting time categories. Over a median follow-up of 8.9 years, 311 participants died, 28% of them due to cardiovascular events. Frail people with prolonged sitting time were at higher risk of all-cause and cardiovascular mortality (hazard ratio 3.13; 95% confidence interval [2.06, 4.71] and hazard ratio 2.41; 95% confidence interval [1.50, 3.64], respectively). The observed risk was higher in women than men. Public health and individual strategies should be implemented to decrease sitting time across the population, with special attention on frail people.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 04/13/2024 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at
https://www.ncbi.nlm.nih.gov/pubmed/38134903
