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Association of Single-Nucleotide Polymorphisms of the MBL2 with Atopic Dermatitis in Korean Patients.

Authors
  • Kim, Jung Soo1
  • Lee, Soo Young1
  • Hahn, Hyung Jin1
  • Lee, Young Bok1
  • Yu, Dong Soo1
  • Kim, Jin Wou1
  • 1 Department of Dermatology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea. , (North Korea)
Type
Published Article
Journal
Annals of dermatology
Publication Date
Oct 01, 2017
Volume
29
Issue
5
Pages
571–577
Identifiers
DOI: 10.5021/ad.2017.29.5.571
PMID: 28966513
Source
Medline
Keywords
License
Unknown

Abstract

The frequency of MBL2 HYPB haplotype was significantly decreased in the AD patients compared to the controls. The frequency of LYPB/LXPA had a possibly protective effect on AD. Moreover, the MBL2 HYPA haplotype pairs, which were related to higher blood total IgE levels, were possibly associated with extrinsic AD.

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