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Association of Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios with In-Hospital Mortality in Patients with Type A Acute Aortic Dissection.

Authors
  • Bedel, Cihan1
  • Selvi, Fatih1
  • 1 University of Health Sciences Antalya Training and Research Hospital Department of Emergency Medicine Antalya Turkey University of Health Sciences, Antalya Training and Research Hospital, Department of Emergency Medicine, Antalya, Turkey. , (Turkey)
Type
Published Article
Journal
Brazilian journal of cardiovascular surgery
Publication Date
Dec 01, 2019
Volume
34
Issue
6
Pages
694–698
Identifiers
DOI: 10.21470/1678-9741-2018-0343
PMID: 31545575
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To evaluate the relationship between neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) with in-hospital mortality in type A acute aortic dissection (AAD). A total of 96 patients who presented to the emergency department between January 2013 and June 2018 with a diagnosis of type A AAD were enrolled in this study. White blood cell count subtypes such as NLR and PLR were calculated at the time of admission. The end point was in-hospital mortality. Of the 96 type A AAD patients included in this analysis, 17 patients (17.7%) died during hospitalization. NLR and PLR were significantly elevated in patients with type A AAD (P<0.001 and <0.001, respectively). Based on the receiver operating characteristic curve, the best NLR cut-off value to predict in-hospital mortality was 9.74, with 70.6% sensitivity and 76.8% specificity, whereas the best PLR cut-off value was 195.8, with 76.5% sensitivity and 78.1% specificity. Admission NLR and PLR levels were important risk factors and independently associated with in-hospital mortality of type A AAD patients.

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