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Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease.

Authors
  • Graff-Radford, Neill R
  • Crook, Julia E
  • Lucas, John
  • Boeve, Bradley F
  • Knopman, David S
  • Ivnik, Robert J
  • Smith, Glenn E
  • Younkin, Linda H
  • Petersen, Ronald C
  • Younkin, Steven G
Type
Published Article
Journal
Archives of Neurology
Publisher
American Medical Association
Publication Date
Mar 01, 2007
Volume
64
Issue
3
Pages
354–362
Identifiers
PMID: 17353377
Source
Medline
License
Unknown

Abstract

The plasma Abeta42/Abeta40 ratio may be a useful premorbid biomarker for identifying cognitively normal elderly white subjects who are at increased risk for developing MCI or AD.

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