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Association of centromeric heterochromatin with the nucleolus in mouse Sertoli cells.

Authors
Type
Published Article
Journal
The Anatomical record
Publication Date
Volume
205
Issue
4
Pages
375–380
Identifiers
PMID: 6859551
Source
Medline
License
Unknown

Abstract

In adult Sertoli cells of most strains of mice, all the centromeric heterochromatin is condensed in two chromocenters, one on each side of a single, large nucleolus. In a random-bred Swiss OF-1 strain, however, the nucleus has a different structural organization. Part of the heterochromatin Is seen as chromocenters in contact with the nucleolus; the rest of it is dispersed in granules of unequal size in the nucleoplasm. Such an unusual spatial arrangement of heterochromatin in interphase nucleus cannot be explained either by a difference in the nucleolar organizing regions or by a polymorphism of the C-banding of metaphase chromosomes.

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