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[Association of breast cancer and cancer of the uterus. 34 case reports].

Authors
  • Le Bouëdec, G1
  • Kauffmann, P
  • Richard, J F
  • Le Roux, S
  • Dauplat, J
  • 1 Service de Chirurgie, Centre Jean Perrin, Clermont-Ferrand.
Type
Published Article
Journal
Revue francaise de gynecologie et d'obstetrique
Publication Date
Mar 01, 1993
Volume
88
Issue
3
Pages
136–141
Identifiers
PMID: 8493440
Source
Medline
Language
French
License
Unknown

Abstract

A retrospective series of 34 cases of breast cancer combined with uterine cancer is reported. Cancers of the endometrium differed from cervical cancers by their number, 2.2 x more frequent (22 vs 10) and by the sequence of onset: they generally precede breast cancer, whereas they tend to follow cervical cancers. In contrast to the breast cancer/uterine cervical cancer association, which is considered to be fortuitous, the breast cancer/cancer of the uterine body association appears to be determined by a hormonal context. Through a review of the literature, a unifying endocrine theory is constructed, based on the role of hyperestrogenesis in mammary and endometrial carcinogenesis.

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