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Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery.

Authors
  • Friedman, Daniel J1, 2
  • Piccini, Jonathan P1, 2
  • Wang, Tongrong3
  • Zheng, Jiayin3
  • Malaisrie, S Chris4
  • Holmes, David R5
  • Suri, Rakesh M6
  • Mack, Michael J7
  • Badhwar, Vinay8
  • Jacobs, Jeffrey P9
  • Gaca, Jeffrey G10
  • Chow, Shein-Chung3
  • Peterson, Eric D1, 2
  • Brennan, J Matthew2
  • 1 Duke Clinical Research Institute, Durham, North Carolina.
  • 2 Duke University School of Medicine, Durham, North Carolina.
  • 3 Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina.
  • 4 Division of Cardiac Surgery, Northwestern University, Chicago, Illinois.
  • 5 Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
  • 6 Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.
  • 7 Division of Cardiovascular Surgery, Baylor University, Dallas, Texas.
  • 8 Department of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown.
  • 9 Hopkins All Children's Heart Institute, St Petersburg, Florida.
  • 10 Division of Cardiovascular and Thoracic Surgery, Duke University, Durham, North Carolina.
Type
Published Article
Journal
JAMA
Publisher
American Medical Association
Publication Date
Jan 23, 2018
Volume
319
Issue
4
Pages
365–374
Identifiers
DOI: 10.1001/jama.2017.20125
PMID: 29362794
Source
Medline
License
Unknown

Abstract

Among older patients with AF undergoing concomitant cardiac surgery, S-LAAO, compared with no S-LAAO, was associated with a lower risk of readmission for thromboembolism over 3 years. These findings support the use of S-LAAO, but randomized trials are necessary to provide definitive evidence.

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