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Assisted Reproductive Technologies and Their Association With Adverse Pregnancy Outcomes and Long-Term Cardiovascular Disease: Implications for Counseling Patients

Authors
  • Park, Ki1
  • Allard-Phillips, Emily2
  • Christman, Gregory2
  • Dimza, Michelle2
  • Rhoton-Vlasak, Alice2
  • 1 University of Florida, 1600 SW Archer Rd, Gainesville, FL, 32610, USA , Gainesville (United States)
  • 2 University of Florida College of Medicine, Gainesville, FL, USA , Gainesville (United States)
Type
Published Article
Journal
Current Treatment Options in Cardiovascular Medicine
Publisher
Springer US
Publication Date
May 25, 2021
Volume
23
Issue
8
Identifiers
DOI: 10.1007/s11936-021-00932-3
Source
Springer Nature
Keywords
License
Yellow

Abstract

Purpose of reviewAssisted reproductive technology (ART) has continued to emerge as a treatment option for infertility, a condition that affects a significant proportion of couples of reproductive age. The goal of this review is to provide information on the link between adverse pregnancy outcomes (APOs) and ART and long-term cardiovascular consequences associated with these therapies.Recent findingsIncreasing use and advancing maternal age have raised concerns regarding the short- and long-term use of such technologies. ART and associated hormonal therapies are known to cause potential vascular effects and have an association with APOs and cardiovascular disease.SummaryOur review highlights potential risks associated with ART and the need for pre-treatment awareness and counseling of short-term APO risk and long-term cardiovascular disease.

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