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Assessment of risk of insect-resistant transgenic crops to nontarget arthropods.

Authors
  • Romeis, Jörg
  • Bartsch, Detlef
  • Bigler, Franz
  • Candolfi, Marco P
  • Gielkens, Marco M C
  • Hartley, Susan E
  • Hellmich, Richard L
  • Huesing, Joseph E
  • Jepson, Paul C
  • Layton, Raymond
  • Quemada, Hector
  • Raybould, Alan
  • Rose, Robyn I
  • Schiemann, Joachim
  • Sears, Mark K
  • Shelton, Anthony M
  • Sweet, Jeremy
  • Vaituzis, Zigfridas
  • Wolt, Jeffrey D
Type
Published Article
Journal
Nature Biotechnology
Publisher
Springer Nature
Publication Date
Feb 01, 2008
Volume
26
Issue
2
Pages
203–208
Identifiers
DOI: 10.1038/nbt1381
PMID: 18259178
Source
Medline
License
Unknown

Abstract

An international initiative is developing a scientifically rigorous approach to evaluate the potential risks to nontarget arthropods (NTAs) posed by insect-resistant, genetically modified (IRGM) crops. It adapts the tiered approach to risk assessment that is used internationally within regulatory toxicology and environmental sciences. The approach focuses on the formulation and testing of clearly stated risk hypotheses, making maximum use of available data and using formal decision guidelines to progress between testing stages (or tiers). It is intended to provide guidance to regulatory agencies that are currently developing their own NTA risk assessment guidelines for IRGM crops and to help harmonize regulatory requirements between different countries and different regions of the world.

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