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Assessment of the regenerative potential of allogeneic periodontal ligament stem cells in a rodent periodontal defect model.

Authors
  • Han, J
  • Menicanin, D
  • Marino, V
  • Ge, S
  • Mrozik, K
  • Gronthos, S
  • Bartold, P M
Type
Published Article
Journal
Journal of Periodontal Research
Publisher
Wiley (Blackwell Publishing)
Publication Date
Jun 01, 2014
Volume
49
Issue
3
Pages
333–345
Identifiers
DOI: 10.1111/jre.12111
PMID: 23841948
Source
Medline
Keywords
License
Unknown

Abstract

The present investigation shows that allogeneic PDLSCs have a marked ability to repair periodontal defects by forming bone, PDL and cementum-like tissue in vivo. The results suggest that treatment periods of 14 and 21 d are optimal end time-points for quantitative assessment of periodontal regeneration within the rodent fenestration-defect model utilized in the present study.

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