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Assessment of the regenerative potential of allogeneic periodontal ligament stem cells in a rodent periodontal defect model.

Authors
Type
Published Article
Journal
Journal of periodontal research
Publication Date
Volume
49
Issue
3
Pages
333–345
Identifiers
DOI: 10.1111/jre.12111
PMID: 23841948
Source
Medline
Keywords
  • Allogeneic Cells
  • Periodontal Ligament Stem Cells
  • Periodontal Regeneration

Abstract

The present investigation shows that allogeneic PDLSCs have a marked ability to repair periodontal defects by forming bone, PDL and cementum-like tissue in vivo. The results suggest that treatment periods of 14 and 21 d are optimal end time-points for quantitative assessment of periodontal regeneration within the rodent fenestration-defect model utilized in the present study.

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