The aim of this study is to evaluate the self-efficacy perceptions and problem solving competencies of students of Health Sciences Faculty. The study included 150 students studying in 4th grade who completed the questionnaire completely. Self-efficacy-competence scale was used to evaluate students’ self-efficacy perceptions, and Problem Solving Inventory was used to evaluate problem solving proficiencies. The mean age of the students included in the study was 22.26 ± 1.27 years and 59.3% [n = 89] were female students. It was determined that the self-efficacy perception scores of the students were 82.30 ± 14.37 and the problem solving ability scores were 103.65 ± 19.31. There was a significant relationship between self-efficacy perception and problem solving ability [r = -0,328, p: 0.01]. According to the results, it was determined that the students had a low level of self-efficacy perception and problem solving competencies.