Affordable Access

Access to the full text

Assessment of cervical elastography strain pattern and its association with preterm birth

Authors
  • Oturina, Vera
  • Hammer, Kerstin
  • Möllers, Mareike
  • Braun, Janina
  • Falkenberg, Maria Karina
  • de Murcia, Kathrin Oelmeier
  • Möllmann, Ute
  • Eveslage, Maria
  • Fruscalzo, Arrigo
  • Klockenbusch, Walter
  • Schmitz, Ralf
Type
Published Article
Journal
Journal of Perinatal Medicine
Publisher
Walter de Gruyter GmbH
Publication Date
Mar 04, 2017
Volume
45
Issue
8
Pages
925–932
Identifiers
DOI: 10.1515/jpm-2016-0375
Source
De Gruyter
Keywords
License
Yellow

Abstract

Objective: The aim of the study was to assess the cervical strain pattern by an ultrasound elastography cervix examination and to determine its association with preterm delivery. Methods: In this study, 30 cases resulting in preterm birth and 30 gestational age-matched controls were included. A vaginal ultrasound examination with cervical length and elastography measurement was performed. We calculated four strain ratios (SR1–SR4) of the regions of interest (ROIs) arranged in pairs in four different positions on the anterior cervical lip. The strain ratios were correlated to the outcome of spontaneous preterm delivery. The inter-observer and intra-observer variability of the strain measurement was evaluated. Results: We observed an association between the value of the strain ratio that was calculated from the ROIs placed side by side in the middle of the anterior lip (SR4), and preterm delivery (P<0.001). The predictive values of cervical length and SR4 were comparable (AUC 0.7394; AUC 0.8322, respectively). The combination of cervical length and SR4 was superior in predicting preterm delivery compared to both parameters alone (AUC 0.8789). The inter-observer and intra-observer variability of data acquisition and measurement was excellent. Conclusions: Our study assesses the cervical elastography strain pattern and shows a correlation to a spontaneous preterm birth.

Report this publication

Statistics

Seen <100 times