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Assessment of biochemical markers in the early post-burn period for predicting acute kidney injury and mortality in patients with major burn injury: comparison of serum creatinine, serum cystatin-C, plasma and urine neutrophil gelatinase-associated lipocalin.

Authors
  • Yang, Hyeong Tae
  • Yim, Haejun
  • Cho, Yong Suk
  • Kym, Dohern
  • Hur, Jun
  • Kim, Jong Hyun
  • Chun, Wook
  • Kim, Hyun Soo
Type
Published Article
Journal
Critical care (London, England)
Publication Date
Jan 01, 2014
Volume
18
Issue
4
Identifiers
DOI: 10.1186/cc13989
PMID: 25023056
Source
Medline
License
Unknown

Abstract

Massively burned patients who maintained high plasma and urine NGAL levels until 12 hours after admission were at the risk of developing early AKI and early mortality with burn shock. However, the plasma and urine NGAL levels in the early post-burn period failed to predict late AKI and non-burn shock mortality in this study. Nevertheless, the plasma and urine NGAL levels were independently associated with AKI development and mortality within 48 hours after admission.

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