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Assessing the impact of additional follow-up in cohort studies.

Authors
  • Brookmeyer, R
  • Day, N
  • Pompe-Kirn, V
Type
Published Article
Journal
American Journal of Epidemiology
Publisher
Oxford University Press
Publication Date
Apr 01, 1985
Volume
121
Issue
4
Pages
611–619
Identifiers
PMID: 4014150
Source
Medline
License
Unknown

Abstract

An approach is described for predicting the statistical value of extending follow-up in a cohort study. A simple approximation to the expected number of new events of interest is given. The effect of these events on inferences for parameters such as a standardized mortality ratio is approached in two ways. The first concerns the probability of reversing the conclusion of a significance test. The second approach finds the plausible range of values for the standardized mortality ratio after further follow-up that are consistent with the currently available data. Each of these values is displayed together with the precision of the estimate. The methods are illustrated with results from the International Radiation Study of Cervical Cancer (IARC Scientific Publication No. 52, 1984).

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