Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

Authors

• Yuan, Yuan¹
• Van Allen, Eliezer M²
• Omberg, Larsson³
• Wagle, Nikhil⁴
• Amin-Mansour, Ali⁵
• Sokolov, Artem⁶
• Byers, Lauren A⁷
• Xu, Yanxun⁸
• Hess, Kenneth R⁹
• Diao, Lixia¹⁰
• Han, Leng¹⁰
• Huang, Xuelin⁹
• Lawrence, Michael S⁵
• Weinstein, John N¹¹
• Stuart, Josh M⁶
• Mills, Gordon B¹²
• Garraway, Levi A¹³
• Margolin, Adam A¹⁴
• Getz, Gad¹⁵
• Liang, Han¹

• ¹ 1] Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USA. [2] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. [3].
• ² 1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3].
• ³ 1] Sage Bionetworks, Seattle, Washington, USA. [2].
• ⁴ 1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
• ⁵ Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
• ⁶ Department of Biomolecular Engineering, University of California, Santa Cruz, California, USA.
• ⁷ Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• ⁸ Division of Statistics and Scientific Computing, The University of Texas at Austin, Austin, Texas, USA.
• ⁹ Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• ¹⁰ Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• ¹¹ 1] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. [2] Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• ¹² Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• ¹³ 1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4].
• ¹⁴ 1] Sage Bionetworks, Seattle, Washington, USA. [2] [3].
• ¹⁵ 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA. [3] Massachusetts General Hospital, Cancer Center and Department of Pathology, Boston, Massachusetts, USA. [4].

Type

Published Article

Journal

Nature Biotechnology

Publisher

Springer Nature

Publication Date

Jul 01, 2014

Volume

32

Issue

7

Pages

644–652

Identifiers

DOI: 10.1038/nbt.2940

PMID: 24952901

Source

Medline

License

Unknown