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Aspirin increases apolipoprotein-A-I-mediated cholesterol efflux via enhancing expression of ATP-binding cassette transporter A1.

Authors
  • Wang, Yu-Hua
  • Chen, Yan-Fang
  • Chen, Shao-Rui
  • Chen, Xi
  • Chen, Jian-Wen
  • Shen, Xiao-Yan
  • Mou, Yong-Gao
  • Liu, Pei-Qing
Type
Published Article
Journal
Pharmacology
Publication Date
Jan 01, 2010
Volume
86
Issue
5-6
Pages
320–326
Identifiers
DOI: 10.1159/000321727
PMID: 21088444
Source
Medline
License
Unknown

Abstract

The data demonstrate that low-dose aspirin increases ABCA1 expression via a PPAR-α-dependent mechanism and increases apoA-I-mediated cholesterol efflux.

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