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Artificial microvascular network: a new tool for measuring rheologic properties of stored red blood cells.

Authors
  • Burns, Jennie M
  • Yang, Xiaoxi
  • Forouzan, Omid
  • Sosa, Jose M
  • Shevkoplyas, Sergey S
Type
Published Article
Journal
Transfusion
Publication Date
May 01, 2012
Volume
52
Issue
5
Pages
1010–1023
Identifiers
DOI: 10.1111/j.1537-2995.2011.03418.x
PMID: 22043858
Source
Medline
License
Unknown

Abstract

The measurements performed using the AMVN device confirm a significant decline in the rheologic properties of RBCs in units nearing expiration and demonstrate the sensitivity of the device to these storage-induced changes. The AMVN device may be useful for testing the effect of new storage conditions, additive solutions, and rejuvenation strategies on the rheologic properties of stored RBCs in vitro.

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