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Arizonins, a new complex of antibiotics related to kalafungin. I. Taxonomy of the producing culture, fermentation and biological activity.

Authors
  • Karwowski, J P
  • Jackson, M
  • Theriault, R J
  • Prokop, J F
  • Maus, M L
  • Hansen, C F
  • Hensey, D M
Type
Published Article
Journal
The Journal of antibiotics
Publication Date
Sep 01, 1988
Volume
41
Issue
9
Pages
1205–1211
Identifiers
PMID: 3182401
Source
Medline
License
Unknown

Abstract

The arizonins, a novel complex of antibiotics related to kalafungin, were discovered in the fermentation broth of Actinoplanes sp. AB660D-122. Comparative taxonomic studies indicated that the culture is a new species and therefore has been designated Actinoplanes arizonaensis sp. nov. Two members of the complex, arizonins A1 and B1, exhibit moderate to potent in vitro antimicrobial activity against pathogenic strains of Gram-positive bacteria.

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