Affordable Access

Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency.

Authors
  • Xia, Chun-hong
  • Liu, Haiquan
  • Chang, Bo
  • Cheng, Catherine
  • Cheung, Debra
  • Wang, Meng
  • Huang, Qingling
  • Horwitz, Joseph
  • Gong, Xiaohua
Type
Published Article
Journal
Investigative Ophthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Publication Date
Jul 01, 2006
Volume
47
Issue
7
Pages
3004–3010
Identifiers
PMID: 16799046
Source
Medline
License
Unknown

Abstract

This work demonstrates that different regions of alphaA-crystallin mediate distinct functions in vivo. These two mutant mouse lines provide useful animal models for further investigating the multiple roles of alphaA-crystallin in the lens.

Report this publication

Statistics

Seen <100 times