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Appropriateness of antiplatelet therapy for primary and secondary cardio- and cerebrovascular prevention in acutely hospitalized older people.

Authors
  • Ardoino, Ilaria1
  • Rossio, Raffaella2
  • Di Blanca, Donnatella3
  • Nobili, Alessandro3
  • Pasina, Luca3
  • Mannucci, Pier Mannuccio4
  • Peyvandi, Flora2
  • Franchi, Carlotta3
  • 1 Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. , (Italy)
  • 2 Department of Pathophysiology and Transplantation, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy. , (Italy)
  • 3 IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy. , (Italy)
  • 4 Scientific Direction, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. , (Italy)
Type
Published Article
Journal
British Journal of Clinical Pharmacology
Publisher
Wiley (Blackwell Publishing)
Publication Date
Nov 01, 2017
Volume
83
Issue
11
Pages
2528–2540
Identifiers
DOI: 10.1111/bcp.13355
PMID: 28722184
Source
Medline
Keywords
License
Unknown

Abstract

This study carried out in acutely hospitalized older people shows a high degree of inappropriate prescription among patients prescribed with antiplatelets for primary prevention, mainly due to overprescription. Further, a large proportion of patients who had had overt cardio- or cerebrovascular disease were underprescribed, in spite of the established benefits of antiplatelet drugs in the context of secondary prevention.

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