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Apparent gastrointestinal origin of cis-4-hydroxycyclohexanecarboxylic acid.

Authors
Type
Published Article
Journal
Clinica Chimica Acta
0009-8981
Publisher
Elsevier
Publication Date
Volume
132
Issue
2
Pages
205–208
Identifiers
PMID: 6616875
Source
Medline

Abstract

We identified by gas chromatography-mass spectrometry the unusual substance cis-4-hydroxycyclohexanecarboxylic acid (4-HCH) in the urine of a child. Urinary excretion of 4-HCH and intestinal bacteria were both suppressed by neomycin treatment. We propose that 4-HCH is a by-product of bacterial metabolism.

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