Affordable Access

deepdyve-link
Publisher Website

Apoptosis induced by SARS-CoV-2: can we target it?

Authors
  • Donia, Ahmed1
  • Bokhari, Habib1
  • 1 COMSATS University Islamabad,
Type
Published Article
Journal
APOPTOSIS
Publisher
Springer-Verlag
Publication Date
Jan 29, 2021
Pages
1–2
Identifiers
DOI: 10.1007/s10495-021-01656-2
PMID: 33512610
PMCID: PMC7844099
Source
PubMed Central
Keywords
Disciplines
  • Letter to the Editor
License
Unknown

Abstract

Some viruses are known to be associated with increased apoptosis. Apoptotic cell death triggered by these viruses has a complex role in host antiviral immunity, and might facilitate the viral clearance or act as a mechanism for virus-induced tissue injury and disease progression. The induction of apoptosis is a hallmark of SARS-CoV-2 infection. Accumulating evidence suggests that there is a direct relationship between apoptosis rate and COVID‐19 pathogenicity/severity. Targeting virus-induced apoptosis could be a promising strategy in the treatment of SARS-CoV-2 virus infection.

Report this publication

Statistics

Seen <100 times