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[ApoE4 increases glycogen synthase kinase 3β expression and Tau phosphorylation in U87 cells].

Authors
  • He, Yan-Jie1
  • Wei, Pei-Ru
  • Wu, Qiao-Yan
  • Zhang, Xin-Yu
  • Zhang, Xing-Mei
  • Liu, Xiao-Jia
  • Wang, Fang
  • 1 Department of Neurobiology, College of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.E-mail: [email protected] , (China)
Type
Published Article
Journal
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Publication Date
Jun 20, 2016
Volume
36
Issue
7
Pages
904–908
Identifiers
PMID: 27435766
Source
Medline
License
Unknown

Abstract

ApoE4 can enhance Tau phosphorylation though upregulating GSK-3β, which sheds light on a new role of ApoE4 in Alzheimer's disease.

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