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Apocynin, a plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis.

Authors
  • Lafeber, F P
  • Beukelman, C J
  • van den Worm, E
  • van Roy, J L
  • Vianen, M E
  • van Roon, J A
  • van Dijk, H
  • Bijlsma, J W
Type
Published Article
Journal
Rheumatology (Oxford, England)
Publication Date
Nov 01, 1999
Volume
38
Issue
11
Pages
1088–1093
Identifiers
PMID: 10556260
Source
Medline
License
Unknown

Abstract

Apocynin in vitro inhibits inflammation-mediated cartilage destruction without having adverse effects on cartilage. The latter may be an advantage of apocynin over many other non-steroidal anti-inflammatory drugs. Therefore, apocynin might have an added beneficial effect in protecting RA patients from joint destruction.

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