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Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.

Authors
  • Kang, Yujung
  • Kim, Jongmin
  • Anderson, Joshua P
  • Wu, Jingxia
  • Gleim, Scott R
  • Kundu, Ramendra K
  • McLean, Danielle L
  • Kim, Jun-dae
  • Park, Hyekyung
  • Jin, Suk-won
  • Hwa, John
  • Quertermous, Thomas
  • Chun, Hyung J
Type
Published Article
Journal
Circulation Research
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jun 20, 2013
Volume
113
Issue
1
Pages
22–31
Identifiers
DOI: 10.1161/CIRCRESAHA.113.301324
PMID: 23603510
Source
Medline
Keywords
License
Unknown

Abstract

Our results demonstrate a novel role for apelin-APJ signaling as a potent regulator of endothelial MEF2 function in the developing cardiovascular system.

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