Affordable Access

Access to the full text

APACHE II Predicts long-term survival in COPD patients admitted to a general medical ward

Authors
  • Goel, Anupam1
  • Pinckney, Richard G.2
  • Littenberg, Benjamin2
  • 1 Wayne State University, Received from the Division of General Internal Medicine, Detroit, Mich , Detroit
  • 2 University of Vermont, the Division of General Internal Medicine, Burlington, Vt , Burlington
Type
Published Article
Journal
Journal of General Internal Medicine
Publisher
Springer-Verlag
Publication Date
Oct 01, 2003
Volume
18
Issue
10
Pages
824–830
Identifiers
DOI: 10.1046/j.1525-1497.2003.20615.x
Source
Springer Nature
Keywords
License
Yellow

Abstract

OBJECTIVE: The Acute Physiology and Chronic Health Evaluation II (APACHE II) was developed to predict intensive-care unit (ICU) resource utilization. This study tested APACHE II’s ability to predict long-term survival of patients with chronic obstructive pulmonary disease (COPD) admitted to general medical floors. DESIGN: We performed a retrospective cohort study of patients admitted for COPD exacerbation outside the ICU. APACHE II scores were calculated by chart review. Mortality was determined by the Social Security Death Index. We tested the association between APACHE II scores and long-term mortality with Cox regression and logistic regression. PATIENTS: The analysis included 92 patients admitted for COPD exacerbation in two Burlington, Vermont hospitals between January 1995 and June 1996. MEASUREMENTS AND MAIN RESULTS: In Cox regression, APACHE II score (hazard ratio [HR] 1.76 for each increase in a 3-level categorization, 95% confidence interval [CI] 1.16 to 2.65) and comorbidity (HR 2.58; 95% CI, 1.36 to 4.88) were associated with long-term mortality (P < .05) in the univariate analysis. After controlling for smoking history, comorbidity, and admission pCO2, APACHE II score was independently associated with long-term mortality (HR 2.19; 95% CI, 1.27 to 3.80). In univariate logistic regression, APACHE II score (odds ratio [OR] 2.31; 95% confidence internal [CI] 1.24 to 4.30) and admission pCO2 (OR 4.18; 95% CI, 1.15 to 15.21) were associated with death at 3 years. After controlling for smoking history, comorbidity, and admission pCO2, APACHE II score was independently associated with death at 3 years (OR 2.62; 95% CI, 1.12 to 6.16). CONCLUSION: APACHE II score may be useful in predicting long-term mortality for COPD patients admitted outside the ICU.

Report this publication

Statistics

Seen <100 times