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[Antizonal antibodies in ovulatory cervical mucus and in serum of patients with fertility disorders].

Authors
Type
Published Article
Journal
Ceská gynekologie / Ceská lékarská spolecnost J. Ev. Purkyne
Publication Date
Volume
69
Issue
3
Pages
215–218
Identifiers
PMID: 15309997
Source
Medline

Abstract

Positive levels of aZP in OM were found in 79 (75.2%) patients, in 56 of them aZP were observed in OM and in serum together, only ovulatory aZPs in 23 (21.9%), and only serum aZPs in 18 (17.1%) were found. aZPs predominate in 47 patients (of 48 women) with more than two in vitro fertilization processes, in thirty of them aZPs in serum and in OM together were observed. On the other hand, repeated spontaneous miscarriage and obesity have no connection with detection of aZPs in our patients. CONCLUSION. The increased levels of serum and OM aZPs are very often seen in patients after repeated unsuccessful IVF. This very important result in reproductive immunology means to go on the micromanipulation technics combined with immunosuppression in the next planned IVF procedure.

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